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CA125 ELISA kit is an immuno-enzymatic colorimetric method for the quantitative determination of the tumoral antigen CA125 concentration in human serum or plasma. CA125 ELISA kit is intended for laboratory use only.
CA125 is a tumour marker, it is a glycoprotein as high molecular weight entity (MW > 200,000). It is best known as a marker for ovarian cancer, but it may also be elevated in other malignant cancers, including those originating in the endometrium, fallopian tubes, lungs, breast and gastrointestinal tract. CA125 may also be elevated in a number of relatively benign conditions, such as endometriosis, several diseases of the ovary and pregnancy. It also tends to be elevated in the presence of any inflammatory condition in the abdominal area, both cancerous and benign. Thus, CA125 is not perfectly specific for cancer nor is it perfectly sensitive since not every patient with cancer will have elevated levels of CA125 in the blood.
CA125 is clinically approved for monitoring the response to treatment and predicting prognosis after treatment. It is especially useful for detecting the recurrence of ovarian cancer. Its potential role for the early detection of ovarian cancer is controversial and has not yet been adopted for widespread screening efforts in asymptomatic women.
Elevated levels in post-menopausal women are usually an indication that further screening is necessary. In pre-menopausal women, the test is less reliable as values are often elevated due to a number of non-cancerous causes.
Model Name:
CA 125
Brand:
DiaMetra
Manufacturer:
Immune Diagnostic System
Origin:
Italy
TECHNICAL DATA
Specification:
Number of tests: 96
Specification:
INCUBATION: 60+15 min
Specification:
SAMPLE TYPE: Serum/Plasma
Specification:
SAMPLE VOLUME: 25 μL
Specification:
ASSAY RANGE: 15 - 400 U/mL
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